Science Article Provides Insights About Ribosome


In the November 4, 2005 issue of the journal Science, LBNL researcher Dr. James Cate and collaborators provided important new insights into the operation of the ribosome, the molecular complex that manufactures proteins in the cell. Dr. Cate and his colleagues determined two high resolution ribosome crystal structures resulting in the first detailed view of the interface between ribosome subunits as well as its center for producing proteins. The research is part of the Genomics:GTL effort to develop strategies to label complexes to track their operation in microbial cells. The National Institutes of Health partially supported this work.